Paulo Mendes' work bridges and hybridizes several fields – cinema, design, architecture, music, theatre, dance, and by the heterogeneity of media that each project determines – painting, drawing, photography, video, installation and performance.

Over the years Paulo Mendes has presented his work at the Serralves Museum, Círculo de Artes Plásticas de Coimbra (CAPC), Museu do Neo-Realismo, Solar Galeria de Arte Cinemática, Chiado Museum, Plataforma Revólver, ZDB Gallery, Culturgest, Quadrum Gallery, Nuno Centeno Gallery, Colégio das Artes - University of Coimbra, Centro Cultural Vila Flor (CCVF), Berardo Museum / CCB, Appleton Square, Museu da Electricidade / Fundação EDP / MAAT, among many other national and international spaces.

Mendes has curated and produced over seventy independent and institutional exhibitions, which marked the development of the work of a new generation of creators and provided him an extensive knowledge of the artistic practice in Portugal